منابع مشابه
B cell-derived cytokines in disease.
B cells regulate immune responses during infectious, inflammatory and autoimmune diseases. Beside their unique and characteristic antibody production, B lymphocytes can modulate physiological and pathological processes by presenting antigens or synthesizing signaling molecules. In human and mouse diseases, immuno-intervention, targeting B cells, has revealed and highlighted their antibody-indep...
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Throughout the monograph, words listed in the glossary are printed in boldface type the first time they appear. This independent study is appropriate for oncology nurses interested in learning about treatment options for B-cell malignancies. After completing this independent study, the participant will be able to • Discuss the role of the CD-20 antigen in B-cell malignancies. • Discuss the role...
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26 donor. This also distinguishes direct NO toxicity from 11,-1 toxicity. In the latter case, ionic fluxes were noted directly after the addition of the cytokine [ 151. In our experiment [CaZ+li started to increase progressively after 30 min until membrane rupture after approx. 3 h (not shown). This progressive calcium ion influx appeared to be closely associated with cell damage because nicoti...
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Natural antibodies (NAbs) are pre-existing antibodies with germline origin that arise in the absence of previous exposure to foreign antigens. NAbs are produced by B-1 lymphocytes and are primarily of the IgM isotype. There is accumulating evidence that - in addition to their role in antimicrobial host defense - NAbs exhibit important housekeeping functions by facilitating the non-immunogenic c...
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The capacity of the trinitrophenyl (TNP) haptenic group, coupled to a series of chemically dissimilar carriers, to cross-stimulate putative T- dependent and T-independent murine B-cell subpepulations was determined by using an in vitro limiting dilution technique to generate primary IgM responses. It was found that TNP-Ficoll and TNP-dextran, two T- independent antigens with little or no polycl...
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ژورنال
عنوان ژورنال: Arthritis Research & Therapy
سال: 2011
ISSN: 1478-6354
DOI: 10.1186/ar3420